On 2007-07-16 Manu Varma, wrote: This book is far and away the clearest and most insightful book on kidney disease. The organization is exceptional, not so much the organization of chapters as the organization of thought that is clear throughout the book. Each disease is explained in a perfect context, making it clear how it´s similar to but different from others (a great antidote to complains that renal diseases ´all look the same and all get steroids anyway´. Well, maybe only an antidote to the first claim...). It explains the tools available and ways to assess kidney disease at just the right level of depth--everything that a clinician would need to know, but not details better suited for pathology textbooks. It´s about twice as long as it´s successor (Renal Pathophysiology: The Essentials) but ten times as insightful.
The curious aspect of reading this book is that it´s now 20 years old. In some ways, it´s prophetic (such as the value of angiotensin blockade), but in other ways, even the pathophysiology discussion is outdated (no mention of E. coli O157:H7 in the section on hemolytic-uremic syndrome). The discussions of therapy are obsolete, but therapy isn´t a major part of a book like this anyway. Even though the brilliance can´t be beat, the book is outdated enough that it probably can´t be used as a single source on kidney disease, so has to serve as a second book for an especially motivated student. An updated edition would get six stars.. And summed up by saying Brilliant. Currently Pathophysiology of Renal Disease has an overall rating of 8 over 10.
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McGraw-Hill Professional claimed Specifically written for students, residents, and practicing physicians, this second edition of has been thoroughly revised and updated to provide a thorough understanding of basic disease mechanisms and a physiologic approach to differential diagnosis. Each chapter contains extensive discussions of pathogenesis, clinical characteristics, differential diagnosis, and treatments of renal disorders.
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